The induction and action of type I interferon (IFN) is of fundamental importance in human immune defenses toward microbial pathogens, particularly viruses.Basic discoveries within the molecular and cellular signaling pathways regulating type I IFN induction and downstream actions have shown the essential role of the IFN regulatory factor (IRF) and
ABSTRACT Manipulating soil metabolism through heavy inoculation with microbes is feasible if organic wastes can be utilized as the substrate for growth and vector as a fertilizer.This, however, requires organisms active in both digestate and soil (generalists).Here, we present a dual enrichment strategy to enrich and isolate such generalists among
The COVID-19 virus has led to a rapid increase in demand for robot service restaurants.However, given the novelty of both, little is known regarding the impact of this technology on Power Banks consumer attitudes in the time of the pandemic.Using a sample of customers with dining experiences in Muscat-based robot service restaurants, the current st
Abstract Inflammation, oxidative damage, and adenosine triphosphate (ATP) depletion play a role in the pathogenesis of cisplatin (CIS)-induced oral mucositis.Objective: The purpose of this research is to examine the impact of ATP against potential oral mucositis development in cisplatin-treated rats.Methodology All rats were randomly assigned to fo
KRAS mutations are one of the most common oncogenic driver mutations in human cancers, Decorative Dish including non-small cell lung cancer (NSCLC), and have established roles in cancer pathogenesis and therapeutic resistance.The development of effective inhibitors of mutant KRAS represents a significant challenge.Three-way junction (3WJ)-based mul